The aim of this thesis was to study hemostatic and genetic risk factors of cardiovascular disease.
To improve our understanding of how hemostatic factors are related to cardiovascular disease we studied the genetic epidemiology of these factors using several novel approaches.
For ADAMTS13 we also studied associations with cardiovascular risk factors, given that these associations remain largely unexplored for this new marker.

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Promotor O.H. Franco (Oscar) , A. Dehghan (Abbas)
Publisher Erasmus University Rotterdam
Sponsor Financial support by the Dutch Heart Foundation for the publication of this thesis is gratefully acknowledged.
ISBN 978-94-6169-799-8
Persistent URL
Note All of the studies described in this thesis involved the Rotterdam Study, which is supported by the Erasmus MC and the Erasmus University Rotterdam, the Netherlands Organization for Scientific Research (NWO), the Netherlands Organization for Health Research and Development (ZonMw), the Dutch Heart Foundation, the Research Institute for Diseases in the Elderly (RIDE), the Ministry of Education, Culture, and Science, the Ministry of Health Welfare and Sports, the European Commission (DG XII), and the municipality of Rotterdam.
de Vries, P.S. (2016, January 20). Hemostasis and Cardiovascular Disease : a molecular epidemiology approach. Erasmus University Rotterdam. Retrieved from